diff --git a/Makefile.am b/Makefile.am
index 7e5485d4c4..6447a39846 100644
--- a/Makefile.am
+++ b/Makefile.am
@@ -422,10 +422,6 @@ if HAVE_Qt
 wireshark_SOURCES = $(WIRESHARK_COMMON_SRC) wireshark-qt.cpp
 
 wireshark_CPPFLAGS = $(AM_CPPFLAGS) $(GLIB_CFLAGS) $(Qt_CFLAGS)
-# Define compatibility macros for Qt 4.8
-if HAVE_QT_VERSION_4
-wireshark_CPPFLAGS += -DQ_NULLPTR=NULL
-endif
 
 wireshark_LDFLAGS = $(AM_LDFLAGS) $(Qt_LDFLAGS)
 
diff --git a/acinclude.m4 b/acinclude.m4
index dd99be03ea..abccee43ab 100644
--- a/acinclude.m4
+++ b/acinclude.m4
@@ -1676,18 +1676,6 @@ AC_DEFUN([AC_WIRESHARK_QT_MODULE_CHECK_WITH_QT_VERSION],
 [
 	case "$3" in
 
-	4)
-		#
-		# Check for Qt 4.
-		#
-		modprefix="Qt"
-		#
-		# Version of the module we're checking for.
-		# Default to 4.0.0.
-		#
-		min_qt_version=ifelse([$2], ,4.0.0,$2)
-		;;
-
 	5)
 		#
 		# Check for Qt 5.
@@ -1695,9 +1683,9 @@ AC_DEFUN([AC_WIRESHARK_QT_MODULE_CHECK_WITH_QT_VERSION],
 		modprefix="Qt5"
 		#
 		# Version of the module we're checking for.
-		# Default to 5.0.0.
+		# Default to 5.2.0.
 		#
-		min_qt_version=5.0.0
+		min_qt_version=5.2.0
 		;;
 
 	*)
@@ -1737,30 +1725,16 @@ AC_DEFUN([AC_WIRESHARK_QT_MODULE_CHECK],
 	#
 	case "$3" in
 
-	yes|unspecified)
+	yes|5)
 		#
 		# Check for all versions of Qt we support.
 		# Try the Qt 5 version first.
 		#
-		versions="5 4"
-		;;
-
-	4)
-		#
-		# Check for Qt 4.
-		#
-		versions="4"
-		;;
-
-	5)
-		#
-		# Check for Qt 5.
-		#
 		versions="5"
 		;;
 
 	*)
-		AC_MSG_ERROR([Qt version $3 is not a known Qt version])
+		AC_MSG_ERROR([$3 is not a known Qt option])
 		;;
 	esac
 
@@ -1769,7 +1743,7 @@ AC_DEFUN([AC_WIRESHARK_QT_MODULE_CHECK],
 		AC_WIRESHARK_QT_MODULE_CHECK_WITH_QT_VERSION($1, $2,
 		    $version, [foundit=yes], [foundit=no])
 		if test "x$foundit" = "xyes"; then
-                        break
+			break
 		fi
 	done
 
diff --git a/configure.ac b/configure.ac
index c445aeeab3..cbc71e6483 100644
--- a/configure.ac
+++ b/configure.ac
@@ -249,9 +249,9 @@ AX_LIB_SOCKET_NSL
 # GUI toolkit options
 #
 AC_ARG_WITH([qt],
-  AC_HELP_STRING( [--with-qt=@<:@yes/no/4/5@:>@],
+  AC_HELP_STRING( [--with-qt=@<:@yes/no@:>@],
 		  [use Qt @<:@default=yes, if available@:>@]),
-  with_qt="$withval", with_qt="unspecified")
+  with_qt="$withval", with_qt="yes")
 
 # GnuTLS
 # Version 3.0 switched from LGPLv2.1+ to LGPLv3+, then switched back to
@@ -1200,12 +1200,7 @@ if test "x$enable_wireshark" = "xyes"; then
 			#
 			case "$host_os" in
 			darwin*)
-				if test $qt_version -le 4
-				then
-					AC_MSG_ERROR([macOS builds should use Qt5])
-				else
-					Qt_LDFLAGS="-Wl,-rpath,"`$PKG_CONFIG --libs Qt${qt_version}Core | sed -e 's/-F//' -e 's/ -framework.*//'`
-				fi
+				Qt_LDFLAGS="-Wl,-rpath,"`$PKG_CONFIG --libs Qt${qt_version}Core | sed -e 's/-F//' -e 's/ -framework.*//'`
 				;;
 			esac
 			AC_SUBST(Qt_LDFLAGS)
@@ -1213,13 +1208,7 @@ if test "x$enable_wireshark" = "xyes"; then
 			if test -z "${MOC_OPTIONS+1}"
 			then
 				# Squelch moc verbose "nothing to do" output
-				if test $QT_VERSION_MAJOR -eq 5
-				then
-					MOC_OPTIONS="-nn"
-				elif test $QT_VERSION_MAJOR -eq 4 -a $QT_VERSION_MINOR -ge 8
-				then
-					MOC_OPTIONS="-nn"
-				fi
+				MOC_OPTIONS="-nn"
 			fi
 			AC_SUBST(MOC_OPTIONS)
 		],
@@ -1493,7 +1482,6 @@ AC_SUBST(wireshark_bin)
 AC_SUBST(wireshark_man)
 AC_SUBST(wireshark_SUBDIRS)
 AM_CONDITIONAL(HAVE_Qt, test "$have_qt" = "yes")
-AM_CONDITIONAL(HAVE_QT_VERSION_4, [test $qt_version -eq 4])
 AM_CONDITIONAL(HAVE_GTK, test "$have_gtk" = "yes")
 
 # Enable/disable tshark
@@ -2635,11 +2623,7 @@ else
 	RPMBUILD_WITH_ARGS="--without gtk2 --without gtk3"
 fi
 if test "x$have_qt" = "xyes" ; then
-	if test "$qt_version" -eq "5"; then
-		RPMBUILD_WITH_ARGS="$RPMBUILD_WITH_ARGS --with qt5"
-	else
-		RPMBUILD_WITH_ARGS="$RPMBUILD_WITH_ARGS --with qt"
-	fi
+	RPMBUILD_WITH_ARGS="$RPMBUILD_WITH_ARGS --with qt5"
 else
 	RPMBUILD_WITH_ARGS="$RPMBUILD_WITH_ARGS --without qt --without qt5"
 fi
diff --git a/packaging/rpm/SPECS/wireshark.spec.in b/packaging/rpm/SPECS/wireshark.spec.in
index 3ddd8a00e8..77fa26e694 100644
--- a/packaging/rpm/SPECS/wireshark.spec.in
+++ b/packaging/rpm/SPECS/wireshark.spec.in
@@ -301,7 +301,7 @@ This package contains the GTK+ Wireshark GUI and desktop integration files.
   --with-extcap=no \
 %endif
 %if %{with qt}
-  --with-qt=4 \
+  --with-qt=5 \
 %else
 %if %{with qt5}
   --with-qt=5 \